Does protein synthesis occur in the nucleus? - ScienceDirect
It's important to realize that the kind of intense, balls-out training most T NATION readers do probably activates protein synthesis to a greater degree than what researchers are using in the lab. Therefore, .
Does protein synthesis occur in the nucleus
The insulin response from carbs may synergistically amplify protein synthesis in the presence of amino acids. Insulin is also a powerful inhibitor of protein degradation.
To make more muscle we need protein, and the type and timing of protein intake during the post-workout period has been shown to control the overall increase in protein synthesis that occurs immediately after training.
What is Protein Synthesis? (with pictures) - wiseGEEK
Ultimately, the string of amino acids folds upon itself, adopting the unique shape that is the signature of that particular protein. Source:
All steps of protein synthesis easily ..
That doesn't mean we should discount carbs as far as protein synthesis goes; they increase insulin levels, which may still be important. Muscles are primed for increased protein synthesis for 24+ hours after training, but the acute burst in protein synthesis that occurs as a result of training or amino acid intake only lasts for a few hours.
Where in eukaryotic cells does mRNA synthesis occur?
Studies have found that both local hyperinsulinemia and the ingestion of carbs inhibits protein breakdown, with little to no effect on protein synthesis. When this was looked at specifically in the post-workout period, it was found that .
Where in the cell does transcription occur
This originally came as quite a surprise, because insulin is a potent activator of protein synthesis. Insulin activates mTOR by way of PI3K/akt signaling, which is parallel to the pathways used by amino acids and mechanical stress to activate mTOR.
Protein Synthesis (part 2): - Biology-Online
True hard-gainers can really benefit from the protein degradation inhibiting effects of insulin here. The big spike in insulin from the high GI carbs and more sustained elevation from medium GI carbs may also keep the protein synthesis throttle open longer.
Where Does Protein Synthesis Take Place? ~ Anabolicco
For instance, one study found that whey protein-induced increases in protein synthesis post-resistance exercise peaked at 20 grams of protein, with larger amounts not increasing the response any further. Similar dose-response studies have been done to determine the maximal requirements for leucine.