Review article and products for sialic acid synthesis and signaling.

Metkinen Chemistry provides unique reagents for DNA and RNA synthesis.

Nucleotide Metabolism: Nucleic Acid Synthesis

Uridine-5'-triphosphate Trisodium Salt, a pyrimidine nucleoside triphosphate, is used as substrate for the synthesis of RNA during transcription. Ungraded products supplied by Spectrum are indicative of a grade suitable for general industrial use or research purposes and typically are not suitable for human consumption or therapeutic use. These materials may or may not have a Certificate of Analysis available.

DNA Polymerase I - Worthington Enzyme Manual

Uridine diphosphate (UDP)-glucose dehydrogenase, the enzyme that converts UDP-glucose to UDP-glucuronic acid, was derepressed in a mucoid (capR9) strain of Escherichia coli K-12 and repressed in a nonmucoid (capR+) strain. A nonmucoid mutant (strain MC 152; capR9 non-2) derived from the mucoid strain accumulated large quantities of nucleotides. Among these nucleotides, UDP-glucuronic acid was identified as well as guanosine triphosphate and an adenosine diphosphate-sugar. UDP-glucose dehydrogenase was still derepressed in strain MC 152. When the nonmucoid mutant was transduced to the wild-type state for this regulator gene (capR+), the transductant was found to accumulate less total nucleotides, and the accumulation of UDP-glucuronic acid was abolished. UDP-glucose dehydrogenase was repressed in the capR+non-2 strain but not to the same extent that it was in the capR+ strain.

Uridine-5'-triphosphate Trisodium Salt, a pyrimidine nucleoside triphosphate, is used as substrate for the synthesis of RNA during transcription. Ungraded products supplied by Spectrum are indicative of a grade suitable for general industrial use or research purposes and typically are not suitable for human consumption or therapeutic use. These materials may or may not have a Certificate of Analysis available.