The Mechanism of the Hinsberg Thiophene Ring Synthesis …

The Mechanism of the Hinsberg Thiophene Ring Synthesis1,2
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The Mechanism of the Hinsberg Thiophene Ring Synthesis 1,2

Background and aim: Spiroazetidin-2-ones and furans are commonly used as anti-bacterial, anti-fungal, anti-inflammatory, cardiovascular activities, anticancer, antiparkinson agents etc. The purpose of this study was to perform virtual toxicity studies of the synthesized compounds 1-(substitutedphenyl)-3-chloro-5,9-bis(furan-2-ylmethylidene)-1-azaspiro[3.5]nonan-2-ones (3a-3h). Materials and method...

Thiophene dendrons and dendrimers were designed and synthesized using a convergent approach
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Thiophene is a heterocyclic compound with the formula C 4 H 4 S

Highly substituted thiophene derivatives first synthesized by Gewald synthesis in 1965, are important heterocyclic compounds present in numerous biologically active compounds. The synthesis of title compounds was carried out by preparing derivatives of Gewald product. In the present study, a series of 2-aminothiophene derivatives were first prepared by Gewald reaction and further converted into 2-...

General Synthesis of Thiophene and Selenophene …
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The thiophene-based azo dyes class of azo dyes have generated considerable interest since its discovery 62 years ago. These dyes have come to be applied to a very large number and variety of fibres and have therefore achieved an importance which is probably greater than the weights used would suggest. The connection between dyeing and fastness properties on the one hand and chemical constitution on the other is in general indefinite. Also, some factors affecting the current application of these dye types are discussed.

General Synthesis of Thiophene and Selenophene-Based Heteroacenes
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