(1.5 moles) of finely powdered m-nitroaniline (Note 1)
The 2-Methoxy-5-nitroaniline is an aromatic base and could be a useful source of diazonium ions for dye synthesis. This intermediate has been used in the preparation of some organic compounds such as (2-Methoxy-5-nitrophenyl) piperidin-2-ylme thylamine by heating under reflux a mixture of 2-bromomethyl piperidine hydrobromide and 2-methoxy-5-nitroaniline for 17 h.
Synthesis of p-Nitroaniline from Aniline.
This page looks in outline at the preparation of phenylamine (also known as aniline or aminobenzene) starting from benzene. The benzene is first converted to nitrobenzene which is in turn reduced to phenylamine.
Sodium nitrite (3.7 g, 0.03 mole) dissolved in 5 mL of water at a temperature of 0-5°C was added dropwise with stirring to the mixture for 20 min. The resulting diazonium salt solution was added slowly to a solution of N-phenylnaphthylamine (5.2 g, 0.024 mole) with vigorous stirring for 5 min. After further stirring for 2 h, the crude product was collected by filtration, washed with water and dried. Recrystallisation from methanol gave brown solid crystals of dye 2c (4.6 g, 58% yield) Rf (ether/acetone 5:1) = 0.75. This procedure was also used to synthesise dye 2d.
Search results for P-Nitroaniline at Sigma-Aldrich
4-Nitroaniline is mainly consumed industrially as a precursor to , an important dye component. The reduction is effected using iron metal and by catalytic hydrogenation.
Synthesis of Cobalt-Complex Azo Dye from 2, 2[Benzene …
Nitroaniline is a used for determining Kamlet-Taft solvent parameters. The position of its UV-visual peak changes with the balance of hydrogen bonding acceptors and donors in the solvent.
How to make P-Nitroaniline - VidInfo
The compound is toxic by way of inhalation, ingestion, and absorption, and should be handled with care. Its in rats is 750 mg/kg when administered orally. 4-Nitroaniline is particularly harmful to all aquatic organisms, and can cause long-term damage to the environment if released as a pollutant.
of good commercial m-nitroaniline, ..
Another compound that has been prepared from 2-methoxy-5-nitroaniline is 2-[(2-Methoxy-5-nitrophenyl amino) methylpiperidin-1-y1] acetic acid ethyl ester. This was done by heating a mixture of 2-methoxy-5-nitrophenyl piperidin-2-yl-methylamine, ethyl bromoacetate and triethylamine in dry ethanol under reflux for 4 h (). Hence, in this present study, we report the synthesis and spectral properties of some monoazo disperse dyes of general structure I derived from 2-Methoxy-5-nitroaniline. Also the solvatochromic behaviour of the dyes in various solvents was evaluated (R is given ).
Synthesis of Cobalt-Complex Azo Dye from 2, 2[Benzene ..
Materials: The 2-Methoxy-5-nitroaniline, 1-hydroxynaphthalene, 2-hydroxynaphthalene, N-phenylnaphthylamine, 1,3-diaminobenzene, 1,3-dihydroxybenzene and 3-aminophenol were purchased from Aldrich chemical company and Fluka chemical company and used without further purification. All other chemicals used in the synthesis and characterization were of laboratory reagent grade.
synthese van p nitroaniline methode 2 - YouTube
The term benzyl describes the radical, ion or functional group C6H5CH2-, derived by removing hydrogen atom from methyl group in toluene, while phenyl is the term for the monovalent radical C6H5-, derived by removal of hydrogen from benzene.