most commonly for lithium orotate ..
Magnesium is involved in energy production and storage, the breakdown of fatty acids, protein synthesis, DNA metabolism, the relaxation of both voluntary and involuntary muscle tissue, neuro-transmitter activity, and hormone regulation.
Lithium orotate, is a salt of orotic acid and lithium
Potassium orotate is a mineral transporter where potassium is bound to orotic acid. Potassium orotate delivers potassium through the cell membrane and into the cell. Dr. Hans Nieper believed this was the most effective potassium transporter for delivering potassium into the cell. The intracellular uptake of potassium helps stabilizes cellular acidity and energy production helps correct glucose metabolism (sugar is a potassium antagonist) and improves low potassium levels in diabetics. Potassium orotate also supports collagen synthesis. Potassium mineral transporters such as potassium orotate, potassium arginate and potassium-magnesium aspartate can be useful in supporting metabolism both in heart muscle and skeletal muscles. Both potassium arginate and potassium orotate are helpful in cellular potassium replacement in individuals suffering from potassium loss due to diarrhea, vomiting, malabsorption, sweating, heavy use of diuretics and prolonged stress.
Orotic acid, the second active ingredient of magnesium orotate, is an intermediate in the biosynthetic pathway of pyrimidines and is shown to improve the energy status of injured myocardium by stimulating, a.o., the synthesis of glycogen and ATP.