Encyclopedia of Reagents for Organic Synthesis || Nickel Boride
The over expression of sLex containing mucins signals the development of gastrointestinal, pancreatic and breast cancer. Therefore, the development of sensors that recognize sLex could help the diagnosis and early detection of cancers. (33) This tetrasaccaride (sLex) contains multiple 1,2 and 1,3 diols making it an ideal binding partner for boron containing sensors. These sensors mimic the action of lectins and have been called boronolectins. (34) Wang et. al. have developed several boronic acids that show a fluorescence intensity increase upon the boronic acid binding with the cell surface saccharide. (35-36)
Handbook of Reagents for Organic Synthesis, Oxidizing and Reducing ..
Forward thinking researchers are increasingly looking to boron containing molecules. This short paper has discussed several applications and uses of boronic acids. All indications point to continued growth in the use of boronic acids. Even as this article is being written more reports are emerging. From its humble beginnings in 1865, to the meteoric rise resulting from Suzuki and Miyaura’s reaction, organoboron compounds are fast becoming compounds used for everything from starting materials to approved drugs. Frontier Scientific stands ready to help researchers create novel chemistries. Give the people at Frontier a call today; the future awaits.
Volatile BN-containing species generated in the molten salt aretransported via a carrier gas to a nickel boride catalyst at 1100°C,whereupon precursor decomposition upon the catalyst material results inthe formation of crystalline boron nitride nanotubes.
CAS No.12007-01-1,Nickel boride (Ni2B) Suppliers
Optically active alcohols and amines are important compounds used extensively as starting materials, intermediates, and chiral auxiliaries for preparing biologically active substances, including natural products. One of the simplest and most useful methods for the preparation of such compounds is the asymmetric reduction of prochiral ketones and ketimines. Boron based reagents have been used to enantioselctively reduce such ketones in a stoichometric and catalytic manner. Both Isuno’s (12) and Corey’s (13) groups discovered oxazaborolidine (OAB)-catalyzed reductions. This reduction furnishes high enantioselectivety with predictable configurations even in the presence of 2 mole% of OAB. More recent work has allowed for these types of reactions to be accomplished using polymer or nickel boride-bound procedures. Having a heterogeneous type catalyst makes this procedure attractive industrially because of the easy of catalyst recovery and separation of products from the reaction mixture. (14-17)
Nickel boride reduction of vanillin oxime - Duration: 14:55
The use of polymer-supported reagents and scavengers provides an attractive and practical method for the clean and efficient preparation of novel chemical entities. These methods can be extended in a multistep fashion to provide access to more complex structures, including biologically active natural products. In our we covered all known supported reagents, catalysts and scavenging agents as useful directory to assist with future synthesis planning in the chemical community. Our group has a long track record in the development and application of polymer-supported reagents in organic synthesis and here we provide a few examples of our work in this area.
Borane-Tetrahydrofurane Complex Reduction of Nickel …
Benzyl esters of a variety of acids can be chemoselectively cleavedon treatment with nickel boride in methanol at ambient temperatureto give the parent carboxylic acids in high yields. Other protectingfunctionalities such as methyl, ethyl, tert-butyl, andtrityl esters as well as benzyl ethers, tert-butylethers, and N-benzylamides are unaffectedunder these conditions.
The electrochemical synthesis of europium boride: ..
Nagasaka and co-workers demonstrated that simple phenylboronic acid can be used to hold the diene and dienophile in such a way that the normal regiocontrol of a Diels-Alder reaction can be inverted. (10) This templating strategy was elegantly exploited in the synthesis of a key intermediate in the total synthesis of Taxol (a powerful anti-cancer agent) by K.C. Nicaolaou and co-workers. (11)