Organic Chemistry: Structure and Nomenclature of Hydrocarbons

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Organic Synthesis Microwave Synthesis Solutions from Biotage

Computer aided drug design is also known as rational drug design it is the process of inventing new medications. Generally the drug will be a organic molecule that may activate or suppress the function of proteins. The type of modeling is often referred to as computer aided drug design. The basic goal in drug design is to predict whether a given molecule will bind to target or not.

Comprehensive Organic Synthesis - 2nd Edition

Organic synthesis is the study of how we build molecules ranging from complex, biologically active natural products to new materials. Because synthesis allows a chemist to construct entirely new structures. It also involving the scientific study of the structure properties and reactions of organic compounds and material. The range of chemical studies in organic chemistry include hydrocarbons.

The synthesis of new molecules with selective activity against tumor cells and which can overcome the problem of drug resistance is of increasing interest. (R)-9-Hydroxystearic acid (9-HSA) is a compound with antineoplastic activity for inhibition of histone deacetylases. The likeness of a 9-HSA part with Vorinostat suggested the synthesis of new 9-HSA derivatives containing the C1-C9-chain linked to heterocycles. 9-HSA will also be esterified with molecules exhibiting antitumor activity. In addition, some Ruthenium complexes have antitumor activity with the benefit of lower toxicity than cis-platinum. Previous studies on the reaction of the Ruthenium complex [(PPh3)3Ru (CO) (H)2] with acetic acid thymine as a nucleobase model suggested the synthesis of similar complexes containing 9-HSA to be tested as an alternative to platinum derivatives. The biological activity of the new compounds will be evaluated by research teams that collaborate with the proposers.

is a valuable compound in the synthesis of new organic compounds.?

studies the mechanism based development of new methods and reagents for the synthesis of fine chemical and pharmacological organic molecules. Target molecular systems include nitrogen and oxygen heterocycles possessing chirality. Our synthetic methods work places a premium on developing economically and environmentally responsible chemistries. Our current studies utilize microwave and organocatalytic methods and are focused on developing asymmetric routes to dihydropyridazines and dihydrophthalazinones and the development of new low cost reagents for the synthesis of carbohydrate and pseudo-carbohydrate targets.

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Heterocyclic, their preparation, transformation, and properties, are undoubtedly a cornerstone of organic chemistry. Several heterocyclic possess excellent biological activity almost without bearing any substituents, which means that their heterocyclic core is definitely part of the pharmacophore. Examples of such scarcely substituted and highly active heterocyclic are the two bipyridyl derivatives such as amrinone which is used in the treatment of congestive heart failure

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focuses on preparing organometallic or transition metal complexes which exhibit catalytic activities. For instance, they prepared some small Fe complexes which mimic the function of Methane Monooxygenase (MMO) by showing highly catalytic activity of C-H oxidation. They identified the key structure required and characterized them by a variety of spectroscopic techniques, magnetic measurements, and X-ray crystallography.

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We supply building blocks for combinatorial chemistry and intermediates for organic synthetic chemistry. Our major products include the kinds of compounds that cannot be found in the major catalogues, such as boronic acids, heteroaromatic acids, amines (primary and secondary) and aldehydes.