An Efficient Microscale Procedure for the Synthesis of Aspirin

A German chemist named Felix Hoffman is credited with being the firstto synthesize aspirin in 1897.

Synthesis of Aspirin2 | Aspirin | Acetic Acid

Further Analysis THE END Presented by MY LIFE: YOU LIGHT IT UP Conclusion The overall objectives of this experiment were to synthesize aspirin, to perform a crude purity test on said aspirin, to standardize and prepare solutions of both NaOH and HCL, and to qualitatively determine the purity of the aspirin by finding the percentage of acetylsalicylic acid in the aspirin.

Data Aspirin was first synthesized by a German chemist named Felix Hoffman in 1897.

Synthesis of Aspirin Lab Report Essay Examples

The ingestion of aspirin after desensitization results in alleviation of chronic upper and lower airway symptoms (30). When the patients were treated with aspirin for 6 months to 6 years a significant reduction in hospitalization, emergency room visits, outpatient visits, and need for nasal/sinus surgery were observed, and in some patients, a reduction in daily oral prednisone doses could be achieved (31). In some patients, significant improvement in nasal and asthma symptoms and reduction in the dose or even discontinuation of oral steroids were already observed (32) within the first four weeks of treatment with aspirin. The clinical benefit is usually seen within the first 6 months of desensitization and continues to be effective for up to 5 years of follow-up. The potential effect of aspirin desensitization and treatment may be limited because: a) not all patients can be desensitized because of the severity or non-stability of underlying asthma, b) desensitization is contraindicated because of concomitant gastric/peptic ulcer disease, c) patients’ drop-out related to gastric intolerance of aspirin, and d) clinical improvement can be achieved in some but not all patients. Considering these limitations, only a fraction of patients with AERD will benefit from aspirin desensitization, and at present it is not possible to identify these patients before the procedure is implemented. Aspirin given after desensitization may be also a valuable solution for ASA-hypersensitive patients requiring chronic treatment with aspirin for rheumatoid diseases or coronary heart disease (33). summarizes indications for ASA-desensitization in patients with asthma and hypersensitivity to NSAIDs.

"Chemistry 104: Synthesis of Aspirin." Chemistry 104: Synthesis of Aspirin.

In the second and third procedures, we prepared a solution of approximately 0.10 M sodium hydroxide (NaOH) and of 0.10 M hydrochloric acid (HCl) to be used in a final back-titration procedure that would quantitatively determine the purity of the aspirin sample.

In the second, place a crystal of powdered commercialaspirin, and in the third, place a crystal of your synthesized aspirin.


Synthesis of Aspirin Ppt | Green Chemistry | Filtration

The result is salicylic acid, as is shown here in this diagram:
Equipment
Chemical Reagents
In the first procedure, our group synthesized a sample of acetylsalicylic acid, otherwise known as aspirin (C9H8O4).

The Synthesis and Analysis of Aspirin ..

125 mL Erlenmeyer Flask Rubber Tubing Calculator...I mean Thermometer Buchner Funnel Assembly Wire Gauze Clamp Test Tubes and Test Tube Rack Ring stand Hot Plate Beakers Goggles Distilled Water Part 1: The Synthesis of Aspirin Step 4 The flask was swirled thoroughly to mix all reagents.

Experimental Procedure: Synthesis of Aspirin ..

Because the aspirin was synthesized from salicylic acid, and the purple color change demonstrated by the addition of ferric chloride indicates the presence of salicylic acid in solution, we determined that the aspirin was not pure and still had remnants of unsynthesized salicylic acid.

Documents Similar To Synthesis of Aspirin Ppt.

Thromboxane (a type of Prostaglandin) stimulates the clotting of platelets when a blood vessel is damaged, and other varieties stimulate blood flow in the endochrinal system, induce labor in the reproductive system, and induce the constriction of bronchi (asthma) in the respiratory system.
Aspirin works against prostaglandins and the effects they have on us by blocking a specific enzyme (cyclooxygenase), which then inhibits the production of prostaglandins, which allows for some of the symptoms to lesson in their effect.
Procedure
1.

Synthesis of Aspirin Lab - YouTube

Disclaimer: The following is a summary of the procedure Iused to make copper aspirinate complex (not compound). I offer it here forinformational purposes to show that copper aspirinate can be made with commonly availablematerials and equipment. A similar procedure is typically done by second-year collegechemistry students as a laboratory exercise in a setting supervised by a professionalinstructor. I do NOT recommend that people do this at home. Some aspects of theseprocedures are hazardous, and the typical home kitchen simply has too many distractionsand interruptions for a student to carry out these procedures safely. Your wife (or mom)will also be furious if you get copper sulfate stains on her kitchen counter!