Experiments and Exercises in Organic Chemistry
Keywords: Organic Chemistry, Collaborative Learning, Cooperative Learning,Inquiry-based, Microbiology, Laboratory Instruction, Multidisciplinary, Antibiotics, Organic Synthesis, Laboratory Experiment
Organic Chemistry: Synthesis of Cyclononallene - …
Research in organic chemistry at MIT addresses a broad spectrum of important problems of current interest and includes investigations at the frontier of bioorganic chemistry, organic synthesis, and materials science. Specific areas of research include protein glycosylation and protein design, chemosensors, continuous flow synthesis, liquid crystals, supramolecular catalysis, the design of new organometallic reagents and catalysts, the invention of new methods for asymmetric catalysis, engineering and pharmaceutical manufacturing, and the development of new strategies for the total synthesis of a wide array of biologically important natural products. A central theme in many projects is the study of structure-reactivity relationships of biological, organic, and organometallic molecules. Much of the current research in the department takes place at the interface of organic chemistry with other areas such as biology, medicine, materials science, and nanotechnology.
The dissociative chemisorption of methane on a metal catalyst is the rate limiting step in the steam reforming of natural gas, our primary source for the molecular hydrogen used in the Haber-Bosch process. In collaboration with the experimental group of Rainer Beck at the École Polytechnic Fédéral de Lausanne, we examined this reaction on a Pt surface containing step defects. We were able to differentiate between reactions at the step edges and the terrace sites, using both UHV molecular beam experiments and high-dimensional quantum scattering theory. Both approaches were also able to resolve the reaction probability with respect to the velocity and vibrational state of the methane molecule and the surface temperature, providing additional details about the reaction mechanism.
1: Synthesis of Aspirin (Experiment) - Chemistry …
Research in organic chemistry at MIT takes place in new, state-of-the-art laboratories in the recently reconstructed Dreyfus Chemistry Building.
Organic Chemistry Labs Experiments ..
The resources available to Organic Chemists are fitting fora laboratory of international stature. Particular emphasis isplaced on , where the diverse facilitiesavailable to researchers are world class. In addition there isa shared Chemistry resource in , permitting rapid and easy acquisition ofstructural data, with all these essential services being covenientlyhoused in the new laboratory. At both the laboratory and Universitylevel the library facilities are excellent, with increasing emphasison electronic access to journals and databases. The location of the journalsand books for the is available online.
Synthesis Experiment 3 | Ligand | Inorganic Chemistry
In this experiment, organic chemistry students synthesized derivatives of their own design of the antibiotic sulfanilamide. The student designs varied from direct modification of sulfanilamide to variations in the preparation of sulfanilamide. After optimizing their synthesis, the organic groups shared their products with the microbiology lab students. The microbiology students used the Kirby-Bauer antibiotic testing method. The students analyzed the derivatives designed by the organic students versus the control antibiotic sulfanilamide. The students used impregnated filter disks on the bacteria and to measure the zone of inhibition after a 24-hour period. The project ended with a joint poster session between the organic and microbiology labs. Students discussed their results and compared them to the control antibiotic sulfanilamide. The experimental results for the student designed derivatives gave zones of inhibition that were comparable to that of sulfanilamide.
Green Chemistry in Organic Synthesis.
Answers to each of these questions fall within the realm of a field known as organicchemistry. For more than 200 years, chemists have divided materials into twocategories. Those isolated from plants and animals were classified as organic,while those that trace back to minerals were inorganic. At one time, chemistsbelieved that organic compounds were fundamentally different from those that wereinorganic because organic compounds contained a vital force that was onlyfound in living systems.