PDF Chemistry 51 Experiment 11 Synthesis and Analysis of Aspirin

Data Aspirin was first synthesized by a German chemist named Felix Hoffman in 1897.

09-The Synthesis and Analysis of Aspirin will be available on

The accuracy of this technique was found to be 卤 3% relative to HPLC and UV/Vis Spectroscopy. A dynamic analysisof the dissolution and subsequent hydrolysis ofaspirin has been determined by in-situ FT-IR. This technique allows ...

Introduction and Purpose Until.Synthesis of Aspirin Lab.

Immunoblot analysisof iNOS expression in the presence ofaspirin showed inhibition of iNOS expression (IC50 = 3 mM). Sodium salicylate variably inhibit...

ofaspirin were shifted or weakened,ever dispeared in both IR and Raman ...CHENG, LiLI, Xiaoman《Chinese Journal of Pharmaceutical Analysis》...

10/10/1998 · Synthesis of Aspirin ..

Ferric Chloride Test for Purity Chemical Reagents: .1M HCl, standardized
.1M NaOH, standardized
95% ethanol
Phenolphthalein solution Step 1 Approximately .5g of the synthesized aspirin was weighed and placed into a 250mL Erlenmeyer flask.

Aspirin Synthesis Formal Lab Report by Dane Brown on …

According to Ramjith et al, flouro, chloro 2-acetyl benzimidazole were prepared by the microwave induced reaction between 3-chloro-4-fluorobenzene-1, 2- diamine and lactic acid, followed by oxidation with potassium permanganate and aluminum oxide. The chalcone derivative of fluoro, chloro-2-acetyl benzimidazole were prepared by the condensation with different aldehydes and the resulting compounds were cyclized with thiourea, to get the thiazine derivatives of fluoro, chloro benzimidazole. The synthesized compounds have been characterized and confirmed by TLC, elemental analysis, IR, and 1H NMR spectroscopy and screened for their antibacterial and analgesic activity. Compounds containing electron withdrawing groups in the substituted Benzimidazole thiazine were found to show potent analgesic and antibacterial activities 21.

chem242 - Lauren's Analysis of IR and HNMR Spectra for Aspirin

Mass Spectrometry Appendixes and Bibliography I Laboratory Equipment II Keeping a Laboratory Notebook III Writing a Laboratory Report IV Calculations for Organic Synthesis V Planning an Experiment VI Properties of Organic Compounds VII The Chemical Literature Bibliography Index.

Experiment 19 synthesis of aspirin and oil of wintergreen

A new series of 4-[{1-(aryl)methylidene}-amino]-3-(4-pyridyl)-5-mercapto-4H-1,2,4-triazolederivative (3a-3f) analogs were designed, synthesized, and characterized. The synthesized compounds were screened for their in-vivo analgesic and anti-pyretic activity. Some of the synthesized compounds 3b, 3c, and 3d exhibited significant analgesic activity and the remaining compounds showed good-to-moderate analgesic activity comparable to that of the standard drug analgin in the tail flick model at 25 mg/kg body weight of the animals. Compounds 3a, 3e, and 3f had a significant anti-pyretic activity comparable with the standard drug aspirin in the yeast-induced pyrexia model at 100 mg/kg body weight.

The synthesis of aspirin is classified as an esterification ..

All the synthesized compoundswere screened for anti-pyretic activity by using the Brewer's yeast-induced pyrexia method[]. Aspirin was used as a reference drug. The anti-pyretic screening results depicted in revealed thatthe compounds 3a, 3e, and 3f significantly decreased the temperature of pyretic (P