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25kg/bag 3-Chloro-4-methylaniline 3,5-Dichloroaniline C 6 H 5 Cl 2 N 96% Min ...

3 essay 4 synthesis dichloroaniline ..

A synthetic scheme is described for chlorinated biphenyl-2,3- and 3,4-catechols to be used as standards for structural assignment of metabolites and protein adducts of 2,2′,5,5′-tetrachlorobiphenyl in which both rings retain chlorine substituents. The scheme has general applicability to the synthesis of chlorinated biphenyl catechols. Dimethyl catechol ethers are coupled to dichloroaniline via the Cadogan reaction to give a library of isomers, followed by demethylation of the ethers with BBr 3 to yield the target catechols. Separation of pure isomers is accomplished by TLC or HPLC prior to or following demethylation, depending on the isomer mixture. [ 2H 3]-Isotopomers are generated using 2,5-dichloroaniline- d 3 as the starting arylamine in the coupling reaction. The dichloroaniline-d 3 hydrochloride is obtained as the sole product from nitration of p-dichlorobenzene-d 4 followed by Pd/C-catalyzed hydrogenation under strongly acidic conditions. This hydrogenation procedure provides a simple and convenient approach to selective reduction of aryl nitro groups in the presence of halogen ring substituents.

Other names: Aniline, 3,5-dichloro-; 3,5-Dichloroaniline Information on this page: Notes ...

4 dichloroaniline 3 synthesis essay Rated 5 / 5 based on 4.3 reviews

Dye application
Dyeing of polyester fabric:
The dye baths were prepared with the synthesized dyes 5-9 using Lignosulphonate (sulphite cellulose liquors) as the dispersing agent. The dyes (1.0 g) were first dissolved in DMF before adding the dispersing agent at Liquor to material ratio of 20:1. The pH of the dye Liquor was adjusted to 5 with acetic acid. Dyeing was performed and continued for 60 min at 130 to 135°C under increased pressures. The dyed polyester fabric was subjected to reduction-cleared treatment at 85°C for 10 min in a solution of sodium hydroxide (flakes) 2 g L-1, sodium sulfite 2 g L-1 and then treated in a betaine amphoteric surfactant in water, washed with water and then dried (; ).

Synthesis of dye 6: Compound 3 (3.0 g, 0.0071 mole) was mixed with 50 mL of water and diazotized with (3.0 g, 0.0183 mole) of sodium nitrite in 15 mL of water in 6 mL of sulph with stirring at 0-5°C over 15 min. 1-Naphthylamine (1.6 g, 0.0057 mole) which was dissolved in 5 mL of acetic acid, was coupled with the resultant diazonium salt solution with vigorous stirring for 2 h. The precipitate obtained was filtered, washed and dried in air. The crude product was recrystallized out of carbon tetrachloride to give a brown solid of compound 6 in 70% yield. This procedure was also used to prepare compound 7.


essay 4 dichloroaniline 3 synthesis

AB - A synthetic scheme is described for chlorinated biphenyl-2,3- and 3,4-catechols to be used as standards for structural assignment of metabolites and protein adducts of 2,2′,5,5′-tetrachlorobiphenyl in which both rings retain chlorine substituents. The scheme has general applicability to the synthesis of chlorinated biphenyl catechols. Dimethyl catechol ethers are coupled to dichloroaniline via the Cadogan reaction to give a library of isomers, followed by demethylation of the ethers with BBr 3 to yield the target catechols. Separation of pure isomers is accomplished by TLC or HPLC prior to or following demethylation, depending on the isomer mixture. [ 2H 3]-Isotopomers are generated using 2,5-dichloroaniline- d 3 as the starting arylamine in the coupling reaction. The dichloroaniline-d 3 hydrochloride is obtained as the sole product from nitration of p-dichlorobenzene-d 4 followed by Pd/C-catalyzed hydrogenation under strongly acidic conditions. This hydrogenation procedure provides a simple and convenient approach to selective reduction of aryl nitro groups in the presence of halogen ring substituents.

Essay 3 4 dichloroaniline synthesis Rated 5 / 5 based on 4.4 reviews

N2 - A synthetic scheme is described for chlorinated biphenyl-2,3- and 3,4-catechols to be used as standards for structural assignment of metabolites and protein adducts of 2,2′,5,5′-tetrachlorobiphenyl in which both rings retain chlorine substituents. The scheme has general applicability to the synthesis of chlorinated biphenyl catechols. Dimethyl catechol ethers are coupled to dichloroaniline via the Cadogan reaction to give a library of isomers, followed by demethylation of the ethers with BBr 3 to yield the target catechols. Separation of pure isomers is accomplished by TLC or HPLC prior to or following demethylation, depending on the isomer mixture. [ 2H 3]-Isotopomers are generated using 2,5-dichloroaniline- d 3 as the starting arylamine in the coupling reaction. The dichloroaniline-d 3 hydrochloride is obtained as the sole product from nitration of p-dichlorobenzene-d 4 followed by Pd/C-catalyzed hydrogenation under strongly acidic conditions. This hydrogenation procedure provides a simple and convenient approach to selective reduction of aryl nitro groups in the presence of halogen ring substituents.

3 5 dichloroaniline synthesis essay - Sky Falcon

m-nitrochlorobenzene|m-chloroaniline|2,5-dichloroaniline|3,4-dichloroaniline--Jiangdu Haichen Chemical Co., Ltd ...