Science of Synthesis. (Journal, magazine, 1998) …

Pfeiffer W. D. In Science of Synthesis, Vol. 35; Schaumann E.,Ed.; Thieme: Stuttgart­, 2007, 423.

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It will provide updates on the latest developments in vascular medicine, complementing Schattauer's established subscription title Thrombosis and Haemostasis.
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O'Connor JE, Costell M, Grisolia S (1987) The potentiation of ammonia toxicity by sodium benzoate is prevented by L-carnithine.

Science of Synthesis News Spring 2007 - Thieme …

In other species, this metabolite appears only after higher doses of about 500 mg/kg body weight (see above) of benzoic acid or sodium benzoate, resulting in a depletion of the glycine pool (Bridges et al., 1970; US FDA, 1972a; Kubota et al., 1988).

Only animals of the third generation were autopsied after 16 weeks, but it is not clear if a complete histopathological investigation was performed.

A highly efficient copper(II)-catalyzed C–S cross-coupling reaction of aryl iodides with tetraalkylthiuram disulfides was developed. With only 1 mol% of CuCl2 as catalyst, zinc powder as reductant, and K2CO3 as base, aryl iodides reacted with tetraalkylthiuram disulfides in DMSO furnishing the corresponding aryl dithiocarbamates in good to excellent yields. This protocol is an improvement of previous work, it features convenient performance, low addition of catalyst, no requirement for any ligand, and provides good yields. The method has a broad substrate scope and uses cheap and readily available starting materials.

However, due to missing experimental details (only results given), the validity of this study cannot be judged.


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Melber, Fraunhofer Institute for Toxicology and Aerosol Research, Hanover, Germany Published under the joint sponsorship of the United Nations Environment Programme, the International Labour Organization, and the World Health Organization, and produced within the framework of the Inter-Organization Programme for the Sound Management of Chemicals.

A mild, general method for conversion of esters to …

0, 375, dosing 750, 1500, 3000, >3000 mg/kg body weight: or 6000 mg/kg mortality about 100% within body weight) 4 weeks; apart from atrophy of the spleen and lymph nodes, no other morphological changes were noted rat; Sherman; 0 or 16-1090 30 adrenals, upper intestine, no adverse effects were Smyth & Carpenter 5 m/f mg/kg body kidney, liver, spleen reported; no further (1948) weight via diet information available mouse; B6C3F1; 0, 2.08, 2.5, or 10 liver, kidney; standard „3750 mg/kg body weight: Fujitani (1993) 4-5 m/f 3% in diet clinical chemistry changes in serum levels (approx.

Asymmetric Total Syntheses of Colchicine, β …

For normal consumers, the uptake of benzoates is about 2-28 times lower than the provisional tolerable intake of 5 mg/kg body weight day, and only in high consumers would this value be exceeded 3 times.

List of important publications in chemistry - Wikipedia

This draft is subject to a peer review in several readings of a working group consisting of representatives from government agencies, the scientific community, and industry.