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Syntheses of R-salbutamol froma racemic mixture:A cheap and easy way to make R-salbutamol is to synthesis a racemicmixture and separate the isomers (either at an intermediate stage or ofthe final products).

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Synthesis of R-Salbutamol fromR-Cyanohydrines:Another synthesis of R-salbutamol reported recently in the literatureis that starting the corresponding R-cyanohydrin.

SYNTHESIS: Drug Design and Discovery: 11, 12. Salbutamol was developed from the modification of Norepinephrine, a natural neuro transmitter. Norepinephrine:
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