Role of DNA in Protein Synthesis - Learn Online at CCC
Frey U, Krug M, Reymann KG and Matthies H (1988) Anisomycin, an inhibitor of protein synthesis, blocks late phases of LTP phenomena in the hippocampal CA1 region in vitro. Brain Research 452(1–2): 57–65.
The role of the genetic code in protein synthesis
: In this animation, you will need to use your knowledge of protein synthesis and DNA structure as you learn how DNA Microarrays are used in experiments.
: This issue of the magazine , includes a great explanation of DNA chips or microarrays. It also includes easy to understand student activities and a teacher's guide. I would strongly recommend printing the entire issue and teacher's guide and using the activities with your students so they can better understand this new technology. In the activities the students use their knowledge of the complementary structure of DNA and protein synthesis to simulate the use of a DNA chip to sequence an unknown strand of DNA and then in another activity they use a chip to determine which form of cancer several patients have by viewing which genes are active so they can prescribe the best treatment for the cancer. ( - AAAS Benchmarks and - )
at the ribosomal site of protein synthesis during ..
: Observe a real world application of protein synthesis as you watch the process in a step by step animation developed by The Genetic Science Learning Center at the University of Utah.
It will also explain the role of genes in protein synthesis
by Lisa Weise, Lori Buwalda, and Barb Neureither
When teaching protein synthesis, you may want to use this activity if you go into more detail. Include the ideas that when the DNA is transcribed into RNA it must then have the sections that represent the introns removed leaving only the exons which makeup the mRNA(click here for more and ). As the human genome project progressed, scientists realized we don't have 100,000 genes as was originally thought. The new estimate became 75,000, then 50,000, then 35,000, and now around 25,000 (it may have changed since this was written). If that is true, then the idea that one gene makes one protein seems impossible since we have more proteins than genes. So how is this possible? Scientists now believe that a single gene can make multiple proteins by splicing together different combinations of their exons. That is what this activity is all about. Using the idea from the previous activity, Protein Synthesis and Words, they make their DNA sequence result in a group of words that can make more than one sentence (protein). By spicing out the introns (nonsense words) and combining different groups of exons (words) they end up with different proteins (sentences).
What are the roles of RNA in protein synthesis in eukaryotes?
: Practice applying your knowledge of protein synthesis at this interactive website developed by The Genetic Science Learning Center at the University of Utah.
What is the role of RNA polymerase in protein synthesis
Primers of genes selected for qRT-PCR; protein abundance and localization of identified proteins in 2-day-old soybean; changed nuclear proteins at 51 h compared to 48 h after sowing; changed nuclear protein under flooding stress for 3 h compared to 48 h after sowing; changed nuclear proteins identified in control and flooding stress with time course manner; identification of protein synthesis related proteins from total protein fraction in soybean under flooding stress for 24 h; procedures of nuclei enrichment; pictures of Western blot analysis for histone H3; principal component analysis of proteomic data; mapping of nuclear pore complex related proteins using KEGG pathway database; cluster analysis of significantly changed nuclear proteins in root tip of soybean in the initial stages of flooding stress; functional distribution of significantly changed nuclear proteins in the identified clusters; agarose gel electrophoresis of qRT-PCR products ()