TRIBAL AND HERBAL MEDICINE USES

BIOLOGICAL ACTIVITIES AND CLINICAL RESEARCH

quantitative-structure activity relationship (QSAR)


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Drug Interactions: None reported.

R., Activity-Based Protein Profiling Reagents for Protein Arginine Deaminase 4 (PAD4): Synthesis and in vitro Evaluation of a Fluorescently Labeled Probe.

Cautions: May cause a measles-like rash in those allergic to the resin.

In all herbal medicine systems where it is employed, copaiba resin is taken internally only in very small dosages-usually only 5-15 drops (approximately one-half to 1 ml) 1-3 times daily. In large doses, it has been documented to cause nausea, vomiting, fever, and a measles-like skin rash. A French dermatologist reported that these side effects can also occur with the absorption of copaiba resin through the skin in sensitive individuals. It has, however, been approved officially in the U.S. as a food additive and is used in small amounts as a flavoring agent in foods and beverages. It has also been employed as a fixative in perfumes.

A Triazole-Templated Ring-Closing Metathesis for Constructing Novel Fused and Bridged Triazoles.


Catalytic Azide-Alkyne Cycloaddition: Reactivity and Applications.

One-Pot Synthesis of 1,2,3-Triazoles from Benzyl and Alkyl Halides, Sodium Azide and Alkynes in Water under Transition-Metal-Catalyst Free Reaction Conditions.

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Pharmaceutical Jurisprudence: D & C Act (Forms, Schedules, Specific area, administration to the act & Different Indian laboratories)

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Surface-Initiated, Atom Transfer Radical Polymerization of Oligo(ethylene glycol) Methyl Ether Methacrylate and Subsequent Click Chemistry for Bioconjugation.

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Pharmacognosy: Herbs as health foods. Herbal cosmetics. Standardization and quality control of herbal drugs, WHO guidelines for the standardization of herbal drugs

A.; Innocenti, A.; Vullo, D.; Supuran, C.

Performance evaluation methods: In-vitro dissolution studies for solid dosage forms methods, interpretation of dissolution data. Bioavailability studies and bioavailability testing protocol and procedures. In vivo methods of evaluation and statistical treatment. GMP and quality assurance, Quality audit. Design, development, production and evaluation of controlled/sustained/extended release formulations.

Design, Synthesis, and Antibody Binding Study.

Biopharmaceutics- Compartment model- ,Clinical Pharmacokinetics: (Full detail of this topic check GPAT-13 syllabus)

B.; Drockenmuller, E.; Hawker, C.

Pharmaceutical Chemistry: Conservation of Orbital Symmetry and Rules: Electrocyclic, Cycloaddition and Sigmatropic reactions; Neighboring group effects; Catalysis by transition metal complexes; Heterocyclic Compounds: Nomenclature, preparation, properties and reactions of 3, 4, 5, 6 & 7-membered heterocycles with one or two heteroatoms like 0, N, S. Chemistry of lipids, Carbohydrates and Proteins.