Protein Synthesis and Translation Activity - Pinterest
In this activity, students use their knowledge of DNA structure, protein synthesis, and mutations to investigate different mutations in the gene known to cause Cystic Fibrosis. This activity helps the students realize that you can have genetic variation within a single gene. That there are multiple alleles for most genes (in fact there are about a thousand alleles for the cystic fibrosis gene) each created by a different mutation for that gene. Some of the mutations cause a change in the protein product and some have no effect. ( - AAAS Benchmarks and - )
Protein Synthesis Bead Lab | BetterLesson
: This issue of the magazine , includes a great explanation of DNA chips or microarrays. It also includes easy to understand student activities and a teacher's guide. I would strongly recommend printing the entire issue and teacher's guide and using the activities with your students so they can better understand this new technology. In the activities the students use their knowledge of the complementary structure of DNA and protein synthesis to simulate the use of a DNA chip to sequence an unknown strand of DNA and then in another activity they use a chip to determine which form of cancer several patients have by viewing which genes are active so they can prescribe the best treatment for the cancer. ( - AAAS Benchmarks and - )
: In this animation, you will need to use your knowledge of protein synthesis and DNA structure as you learn how DNA Microarrays are used in experiments.
Glossary | Linus Pauling Institute | Oregon State University
: Brush up on your understanding of heredity, DNA, genes, traits, chromosomes and proteins at this interactive website developed by The Genetic Science Learning Center at the University of Utah.
: Review your understanding of the structure of DNA and how it replicates as you build a DNA molecule at this interactive website developed by The Genetic Science Learning Center at the University of Utah.
All about protein: What is it and how much do you need?
by Lynn MarieWartski
Protein synthesis, the process of genes contributing to a phenotype, is complex and can be difficult for students to learn. Watching their teacher demonstrate their understanding of it while they teach is not enough for the students to truly understand what is going on at the cellular and molecular levels. They need to practice using these ideas, making mistakes and learning from them, in an environment with some support, before they are expected to use these concepts on their own when encountering new phenomena. This is a great activity to allow students to do just that as they work with a model of protein synthesis that involves their entire classroom. The teacher's desk is the nucleus containing the DNA sequences. In teams of 3, student 1 becomes the mRNA when they transcribe the DNA in nucleus and return to student 2, the ribosome. The ribosome (student 2) writes out the needed tRNA sequence to match the mRNA. Student 3, tRNA, looks for the correct sequence in the cytoplasm (classroom) and when they find it they flip up the card to reveal a word (amino acid). They return to the ribosome with their word (amino acid) to build a sentence (protein). The number of sentences you have your students work through would depend on when it takes them to get comfortable with this process before they move on to examine different types of mutations.