Electrochemically induced synthesis of poly(2,6-carbazole)

SYNTHESIS OF HIGH MOLECULAR WEIGHT POLY(CARBAZOLE)S VIA CLICK POLYMERIZATION[J].

Synthesis of Carbazole-containing Aromatic Polyamide …

N2 - A series of novel carbazole-azo binary compounds was synthesized by modifying 9H-carbazole. The permanent dipole moments of their ground states were estimated by Fishtine method. A simple way generated from solvatochromic method was successful to calculate their first hyperpolarizabilities in the order of 10-28esu, which are comparable with Disperse Red 1 (DR 1). The first hyperpolarizability was highly related to the structure of the related carbazole-azo binary compound. Using their doped poly(methyl methacrylate) (PMMA) films, a refractive index change of these films was determined up to 0.0010 at the incident wavelength of 632.8nm in the two-photon holography experiment. This demonstrated that these compounds exhibited a strong two-photon behavior.

9-Vinylcarbazole CAS#: 1484-13-5 - ChemicalBook

AB - A series of novel carbazole-azo binary compounds was synthesized by modifying 9H-carbazole. The permanent dipole moments of their ground states were estimated by Fishtine method. A simple way generated from solvatochromic method was successful to calculate their first hyperpolarizabilities in the order of 10-28esu, which are comparable with Disperse Red 1 (DR 1). The first hyperpolarizability was highly related to the structure of the related carbazole-azo binary compound. Using their doped poly(methyl methacrylate) (PMMA) films, a refractive index change of these films was determined up to 0.0010 at the incident wavelength of 632.8nm in the two-photon holography experiment. This demonstrated that these compounds exhibited a strong two-photon behavior.

Previous work from our laboratory shows that compounds with two cations linked by a carbazole spacer were highly potent anti-P. carinii agents. A prodrug approach designed to increase oral activity of the dicationic carbazoles by converting amidine groups to amidoxime groups was unsuccessful. The ring nitrogen was implicated as playing a role in the lack of activity of carbazole amidoximes. The current study was designed to determine if replacement of the carbazole ring nitrogen by isosteric oxygen to form dibenzofurans would improve effectiveness of amidoxime prodrugs. Eight dibenzofuran dicationic derivatives were synthesized and evaluated for anti- P. carinii activity in an immunosuppressed rat model. Since DNA binding has been hypothesized to play a key role in antimicrobial activity of dicationic compounds, the compounds were examined for their binding affinity to calf thymus DNA and a poly-dA·poly-dT oligomer. While several of the compounds were more potent anti-P. carinii agents than pentamidine, the corresponding amidoximes were significantly less effective than the amidoxime of pentamidine. No direct quantitative correlation was determined between DNA binding affinity and anti-P. carinii activity, but all active compounds were strong DNA binding agents.