marine pollution | Journal of Medical Thesis
Acetylcholine is a cholinergic neurotransmitter. It is predominant at the neuromuscular junction. Now it is seen that the activity of Acetylcholinesterase is inhibited by several neurotoxic contaminants like heavy metals like Cd, Pb, Hg, etc., organophosphorous pesticides, etc.
In in-vitro conditions experiments were performed to see the effects of different neurotoxic contaminants on marine organism, i.e., a snail (Nerita chamaeleon) and a fish (Etroplus suratensis). Result suggests that DDVP is highly toxic followed by Ethyl Parathion in case of Nerita chamaeleon. In comparison to DDVP & Ethyl Parathion, Phosphoamidon and Methyl Parathion is less toxic. The low toxicity of Phosphoamidon is due to the presence of phenyl group. The phenyl group adds to the stability of the compound.
In case of Etroplus suratensis, Methyl Parathion is the most toxic followed by Monocrotophos, Phosphoamidon and Ethyl Parathion. Here it is seen that DDVP is the least toxic as compared to Nerita chamaeleon. The toxicity of Methyl parathion in this case is about 0.15 whereas in case of Nerita chamaeleon the toxicity of Methyl parathion is about 0.032.
Another set of observations were taken to see if there is any synergistic effect of the pesticides takes place in case of Etroplus suratensis and was found that the level of toxicity goes high when two pesticides are mixed together. Compared to the combination of Ethyl parathion & Methyl parathion, the combination of DDVP & Phosphoamidon is higher.
Thesis about marine pollution by Diana Palacio - issuu
In view of the ongoing problem of marine pollution due to neurotoxic contaminants it is indeed a prime need of the hour to assess the impact of such contamination by toxic compounds using various biomarker techniques. To evaluate the toxicological impact of various types of contaminants, I have been prompted to undertake a systematic study on biomarker of pollution. The main aims and objective the present studies are as follows:
4. To determine activity of acetylcholinesterase activity by Delta pH-metric Method
5. To evaluate the inhibitory effects of various neurotoxic contaminants on acetylcholinesterase activity.
6. To assess impact of neurotoxic contaminants on marine fishes along the Goa coast in terms of acetylcholinesterase activities.
Thesis Question: 1. To determine activity of acetylcholinesterase activity.
2. To evaluate the inhibitory effects of various neurotoxic contaminants on acetylcholinesterase activity.
3. To assess impact of neurotoxic contaminants on marine fishes along the Goa coast in terms of acetylcholinesterase activities
Thesis Answer: Current sets of observations show that the study of Acetylcholinesterase enzyme can help the Eco-toxicologists to assess the impacts of various lethal & sub-lethal pollution in the marine environment. Study of different marine organisms like molluscs, fish, echinoderms, etc. can help to assess the biological effects of the neurotoxic contaminants on marine & estuarine environment.