but when it comes to LSD not so much [video=youtube; ..

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Synthesis of LSD from 1,3-butadiene | Chegg Tutors

LSD is one of the most powerful hallucinogenic drugs known. It was invented in 1938 by the Swiss chemist, Albert Hoffman, who was interested in developing medicines from compounds in , a fungus that attacks rye. Although LSD is purely synthetic, clues to its biological activity can be found by tracing the history of the fungus from which it is derived.

Albert Hofmann, the Father of LSD, Dies at 102 - The …

So, in the spring of 1943, he repeated the synthesis of LSD-25. Quoted below is his entry for this experiment in his laboratory journal of April 19, 1943.

400 People Microdosed LSD for a Month in the Name of Science - "data presented at the MAPS conference was culled from the reports of 418 volunteers"