A visual tutorial on the synthesis of gold nanoparticles
A green and size-controlled synthesis of silver nanoparticles (Ag NPs) in aqueous solution with the assistance of L-cysteine is presented. The size of Ag NPs decreases with the increase of L-cysteine concentration, and thus can be controlled by adjusting L-cysteine concentration. TEM analysis shows that Ag NPs with an average size of 3 nm can be produced in the presence of 1.0 mmol/L L-cysteine, about one sixth of the size of Ag NPs obtained in the absence of L-cysteine (17 nm). The as-synthesized silver colloidal solution is stable and can be stored at room temperature for at least two months without any precipitation. This L-cysteine assisted method is simple, feasible and efficient, and would facilitate the production and application of Ag NPs.
Synthesis and Properties of Tadpole-Shaped Gold Nanoparticles
Photo-reduction of aqueous [AuCl4]- solution to the goldnanoparticles (AuNPs) has been applied as a model process for optimizingthe experimental procedures, and evaluating the potential of shapedlaser pulses in the synthesis of AuNPs.
224. Sasidharan S, Bahadur D, Srivastava R. Protein-Poly(amino acid) Nanocore-Shell Mediated Synthesis of Branched Gold Nanostructures for Computed Tomographic Imaging and Photothermal Therapy of Cancer. 2016;8:15889-903
syntheses of shape controlled gold nanoparticles is that they
Femtosecond laserirradiation has not yet been widely applied for nanoparticle synthesis,and offers new regimes of energy deposition for synthesis ofnanomaterials.
Size Controlled Synthesis of Gold Nanoparticles using ..
The procedure presented in this work is a newconvenient room temperature route for synthesis of small nanoparticles,and its application can be extended to the formation of other transitionmetals and alloy nanoparticles.
The properties of colloidal gold nanoparticles, ..
Control of nanoparticle shape may initially seem like a scientific curiosity, but its goal goes far beyond aesthetic appeal. The shape not only influences the chemical and optical properties of metal nanoparticles, but also their relevance for medical applications. By changing the shape from spherical to branched, one can change the absorption wavelength from visible to near-infrared. These nanoparticles are useful for hyperthermia treatment of cancer cells. Firstly, it is important to synthesize nanoparticles with special shapes in a controlled way. Secondly, these nanoparticles need to be coated with functional groups for the covalent binding of biomolecules (antibodies). An excellent way to functionalize these nanoparticles is by the use of self-assembled monolayers of thiols with general formula: HS-(CH2)n-PEOm-X. HS- binds covalently to gold nanoparticles, -(CH2)n- is a spacer of carbon atoms, -PEOm- is a spacer which allows better water solubility and avoids non-specific adsorption of undesired biomolecules and -X is a functional group for the attachment of biomolecules. This research describes the successful synthesis of functionalized non-spherical nanoparticles which were stable for several months while the not-SAM-coated nanoparticles relaxed to spherical ones after several days. Finally, the applicability of these nanoparticles was studied in preliminary in vitro tests.
Size-controlled synthesis of monodispersed gold nanoparticles ..
Biosafety is the primary concern in clinical translation of nanomedicine. As an intrinsic ingredient of human blood without immunogenicity and encouraged by its successful clinical application in Abraxane, albumin has been regarded as a promising material to produce nanoparticles for bioimaging and drug delivery. The strategies for synthesizing albumin-based nanoparticles could be generally categorized into five classes: template, nanocarrier, scaffold, stabilizer and albumin-polymer conjugate. This review introduces approaches utilizing albumin in the preparation of nanoparticles and thereby provides scientists with knowledge of goal-driven design on albumin-based nanomedicine.