of biological psychology, 2001 (diathesis-stress model)"

202 (diathesis-stress hypothesis)

202 (diathesis-stress hypothesis)

AB - A wealth of clinical data supports a major role of genetic liability as well as of altered brain dopamine (DA) functioning in different types of behavioural disturbances. Genetic influence on behaviour involves multiple genes, rather than one or two major genes, as well as non-genetic sources of variance. Thus, in recent years, increasing attention has been devoted to the involvement of stressful experiences (life events) in the development and expression of psychopathology. Moreover, a diathesis-stress hypothesis has been proposed, which suggests that the environmental factors (stress) are not specific for a given pathology, whereas genetic factors (diathesis) are. Results obtained in an animal model offer support to this hypothesis. Indeed, mice of the C57BL/6 and DBA/2 inbred strains are equally susceptible to stress but develop different behavioural disturbances related to different alterations of brain DA receptors. Moreover, quantitative trait loci (QTL) associations in the C57 (B) x DBA (D) recombinant inbred (RI) strains indicate a number of provisional QTLs influencing the behavioural effect of stress. Finally, the results of this analysis suggest the involvement of regulatory factors related to stress response and neural or synaptic plasticity in the control of brain DA receptor plasticity.

Diathesis-stress model (Psychology)).

Diathesis Stress Theory - Schizophrenic

Chronic Cortisol Exposure Causes Mood Disorders ; Psychology Definition of DIATHESIS -STRESS MODEL : Theory stating that mental and physical disorders develop from genetic or biological.

Also known as diathesis-stress hypothesis.    Define tumor diathesis   And?

A few years later Caspi et al. (2005) took this genetic approach and assessed the catechol-O-methyltransferase (COMT) gene. Their rationale for this is that COMT is involved in the metabolism of dopamine in the prefrontal cortex and dopaminergic deregulation is thought to play a role in the pathogenesis of schizophrenia. The authors concluded that the link between cannabis and psychosis was moderated by a COMT gene polymorphism. That is, cannabis users in their teen years who carried the COMPT valine allele were the most likely to develop psychotic symptoms. On the other hand, teens with two copies of the methionine allele did not present this risk even when using cannabis. This study presented some strong evidence for the stress diathesis model of cannabis and psychosis.

Beck's cognitive theory of depression: The diathesis-stress and causal mediation components.


Diathesis Stress Model Psychology | Flow Psychology

N2 - A wealth of clinical data supports a major role of genetic liability as well as of altered brain dopamine (DA) functioning in different types of behavioural disturbances. Genetic influence on behaviour involves multiple genes, rather than one or two major genes, as well as non-genetic sources of variance. Thus, in recent years, increasing attention has been devoted to the involvement of stressful experiences (life events) in the development and expression of psychopathology. Moreover, a diathesis-stress hypothesis has been proposed, which suggests that the environmental factors (stress) are not specific for a given pathology, whereas genetic factors (diathesis) are. Results obtained in an animal model offer support to this hypothesis. Indeed, mice of the C57BL/6 and DBA/2 inbred strains are equally susceptible to stress but develop different behavioural disturbances related to different alterations of brain DA receptors. Moreover, quantitative trait loci (QTL) associations in the C57 (B) x DBA (D) recombinant inbred (RI) strains indicate a number of provisional QTLs influencing the behavioural effect of stress. Finally, the results of this analysis suggest the involvement of regulatory factors related to stress response and neural or synaptic plasticity in the control of brain DA receptor plasticity.

Diathesis-stress hypothesis of mental illness

A wealth of clinical data supports a major role of genetic liability as well as of altered brain dopamine (DA) functioning in different types of behavioural disturbances. Genetic influence on behaviour involves multiple genes, rather than one or two major genes, as well as non-genetic sources of variance. Thus, in recent years, increasing attention has been devoted to the involvement of stressful experiences (life events) in the development and expression of psychopathology. Moreover, a diathesis-stress hypothesis has been proposed, which suggests that the environmental factors (stress) are not specific for a given pathology, whereas genetic factors (diathesis) are. Results obtained in an animal model offer support to this hypothesis. Indeed, mice of the C57BL/6 and DBA/2 inbred strains are equally susceptible to stress but develop different behavioural disturbances related to different alterations of brain DA receptors. Moreover, quantitative trait loci (QTL) associations in the C57 (B) x DBA (D) recombinant inbred (RI) strains indicate a number of provisional QTLs influencing the behavioural effect of stress. Finally, the results of this analysis suggest the involvement of regulatory factors related to stress response and neural or synaptic plasticity in the control of brain DA receptor plasticity.

Diathesis-stress hypothesis of schizophrenia

Film buffs will recognize that the subheadings in this article are movie titles. In keeping with that theme, I will close by saying that longitudinal em­piri­cal work, guided by theoretical insights and based on sound measurement, is our best bet and, perhaps, our only ticket to an entirely new film, titled “Diathesis-Stress Theories: The Next Generation.”