Adipocyte stress: the endoplasmic reticulum and metabolic disease ..
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adapting to meet the demands of increased protein synthesis ..
Controversially, NKX2-1 pathway activation in lung cancers is associated with poor survival and cisplatin resistance if or pathways are activated at the same time.
The transactivation capacity of NKX2-1 regarding the expression of SP-B is controlled by the sphingolipid ceramide which is produced in inflammation and reduces NKX2-1 binding capacity to the SP-B promoter.
Volcanoes and volcanology | Geology
, , , . Temperature Dependence of CN and SCN IR Absorptions Facilitates Their Interpretation and Use as Probes of Proteins. Analytical Chemistry 2015, 17;87(22), 11561-7. doi:
Jin Kim Montclare, PhD | NYU Tandon School of …
Noodleman, L., Lovell, T., Han, W.-G., Li, J., Himo, F. Quantum Chemical Studies of Intermediates and Reaction Pathways in Selected Enzymes and Catalytic Synthetic Systems. Chem. Rev. 104, 459-508, 2004.
the N-terminal of maltose binding protein from ..
Himo, F., Lovell, T.A., Hilgraf, R., Rostovstev, V.V., Noodleman, L., Sharpless, K.B., Fokin, V.V. Copper(I) -Catalyzed Synthesis of Azoles.
DFT Study Predicts Unprecented Reactivity and Intermediates. J. Am. Chem. Soc. 127, 210-216, 2005.
The protein was expressed with an N-terminal GST tag as ..
Noodleman, L., Han, W.-G. Structure, Redox, pKa, Spin. A Golden Tetrad for Understanding Metalloenzyme Energetics and Reaction Pathways. J. Biol. Inorg. Chem. 11, 674-694, 2006.
PLOS ONE: Relaxed Rotational and Scrunching Changes …
Toutchkine, A., Han, W.-G., Ullmann, M., Liu, T., Bashford, D., Noodleman, L., Hahn, K.M. Experimental and DFT studies: novel structural modifications greatly enhance the solvent sensitivity of live cell imaging dyes. J. Phys. Chem. A 111:10849, 2007.
Epigenetic inheritance of proteostasis and ageing | …
It is expressed in conducting airways type II alveolar epithelial cells and Clara cells and uniformly in the terminal respiratory unit.
NKX2-1 expression is also found in thyroid follicular cells and both normal and hyperplastic C cells where it activates calcitonin gene expression.
NKX2-1 is not expressed in adult neurons of the basal ganglia.