Multistep Synthesis Chemistry Experiment - StudyMode
Keywords: Organic Chemistry, Collaborative Learning, Cooperative Learning,Inquiry-based, Microbiology, Laboratory Instruction, Multidisciplinary, Antibiotics, Organic Synthesis, Laboratory Experiment
Do you have any good suggestion for a chemistry science experiment?
Chemistry: “Kinetics--rate laws from experimental data”. Chemical kinetics. Determining the rate law from experimental data through the method of initial rates. Exponents, rate constant, units for the rate constant. Order of the reaction
Kavanaugh, J.S. et al. "High-resolution x-raystudy of deoxyhemoglobin Rothschild 37beta trp->arg: amutation that creates an intersubunit chloride-bindingsite," (1992) Biochemistry, 31,4111. Deoxyhemoglobin PDB coordinates, Brookhaven ProteinData Bank.
Synthesis Reaction Definition and Examples - ThoughtCo
An experiment is described that is suitable for the early portion of the laboratory in a general chemistry course and integrates organic examples. It is the two-step synthesis of aspirin starting from oil of wintergreen. The mechanism for this synthesis provides examples of three major classes of chemical reactions: hydrolysis, condensation, and proton transfer. To understand the chemistry, the student must be able to recognize the common molecular framework shared by oil of wintergreen, salicylic acid, and aspirin and to identify the -OH and -CO2 sites where chemical changes occur. The experiment differs in three ways from traditional aspirin synthesis experiments for general chemistry. It is designed to be performed early rather than late; it starts from a naturally occurring material and requires two steps rather than one; and it utilizes FTIR spectroscopy to distinguish among oil of wintergreen starting material, salicylic acid intermediate, and aspirin product. The use of FTIR spectroscopy introduces students to a modern analytical technique that is currently used in research involving aspirin.