Brazilian Meeting on Organic Synthesis: 1 ..
Frequently met multiphasic examples include enzymatic reactions (organic–aqueous phases), slurries (solid–liquid), or hydrogenation (solid–liquid–gas)—each requiring effective mixing and long residence times.
Proceedings of the 14th Brazilian Meeting on Organic Synthesis ..
In this review, we use selected examples to demonstrate how continuous methods of synthesis can be greener than batch synthesis on a small and a large scale.
This work culminates in an approach to the telescoped synthesis of (E/Z)-tamoxifen using continuous-flow organometallic reagent-mediated transformations.