Grignard Synthesis: Synthesis of Benzoic Acid - Odinity

In practical food preservation, the Na salt of benzoic acid is the most widely used form (see ).

To Gringnard Triphenylmethanol and Benzoic Acid-2 ..

When used as a preservative, benzoic acid increases storage stability and reduces corrosion for emulsions, polishes, waxes, paints and liquid detergents.

Selective  in vivo inhibition of rat mammary 7,12-dimethylbenz[alpha]anthracene - DNA adduct formation by dietary butylated hydroxytoluene.

Synthesis of Benzoic Acid using a ..

Hydroxylation of BHT- tBuOH occurred at the benzylic methyl position, and the resulting diol was oxidized further to the hydroxybenzaldehyde derivative.

Effect of benzoic acid, sodium benzoate, sorbic acid and potassium sorbate on the activity of catalase and peroxidase of seedlings of Lepidium sativum L].

Discovery of a novel series of benzoic acid derivatives …

Some 34 to 53% of the 14C-label in the bile was identified as 3-5-di- t-butyl-4-hydroxy-benzoic acid, which was probably present as the ester glucuronide.

Benzoic Acid/chemical synthesis*

In the synthesis of high-purity chemical intermediates for the food,cosmetic and pharmaceutical industries only the purest grades of benzoic acid can be used.

Benzoic acid, 2-[ (2'-cyano[1,1 ..

Collect the precipitate by vacuum filtration. Dry the product as thoroughly aspossible, weigh it, and recrystallize it from hot water. (The ether layer contains neutralnon-polar compounds such as unreacted bromobenzene and biphenyl. It should be discardedinto the ORGANIC WASTE bottle.) Calculate the yield of benzoic acid. Take a sample of therecrystallized material and determine its melting point. (Place the remainder of yourbenzoic acid in the jar provided.)

Discovery of a novel series of benzoic acid derivatives as …

[IF NO precipitate forms, then likely some ether is present on the surface of yourbenzoic acid solution. Gently blow off the ether on the acidified solution until crystalsappear. Continue to cool in ice bath until precipitation is complete.]

Benzoic Acid/chemical synthesis* Benzoic …

AB - The catalytic conversion of benzoic acid to phenol in the presence of water and oxygen was studied in the vapor phase over nickel oxide on various supports. NiO/SiO2 was the most selective, and the selectivity reached over 50% using iron oxide and sodium oxide modifiers. Ni-Fe oxide prepared by coprecipitation deactivated with time-on-stream, but that prepared using a cellulose templating method was more stable. Benzene was often a significant by-product. Some coupling products were formed, including xanthone, fluorenone, and biphenyl. From deuterium isotope labeling experiments, the hydroxyl group was found to be formed at the carbon next to the one with the carboxylic acid group.


BHT was a moderately effective inhibitor of benzidine-induced mutagenicity in Salmonella typhimurium strain TA98, activated with a hamster liver S-9 fraction (Josephy et al., 1985).