Nucleophilic Addition Rxns of Aldehydes and Ketones
Organic chemistry: “Alcohols, oxidation, and reduction”. Oxidation of alcohols (PCC). Reduction of and with to form alcohols. Synthesis with . Reduction of with NaBH4 or LiAlH4 to form alcohols.
Alcohols, Synthesis and Reactions
A second general ether synthesis, alkoxymercuration, is patterned after the . Reactions #3 and #4 are examples of this two-step procedure. Note that the alcohol reactant is used as the solvent, and a trifluoroacetate mercury (II) salt is used in preference to the acetate (trifluoroacetate anion is a poorer nucleophile than acetate). The mechanism of alkoxymercuration is similar to that of oxymercuration, with an initial anti-addition of the mercuric species and alcohol being followed by reductive demercuration.
Organic chemistry: “”. of alcohols (PBr3, SOCl2). (, alkyl , ). Using the technique to solve synthesis problems involving (Gilman reagents).