"Total Synthesis of (–)-Nakadomarin A" P.
"Expeditious and Divergent Total Syntheses of Aspidosperma Alkaloids Exploiting Iridium(I)-Catalyzed Generation of Reactive Enamine Intermediates" P.
"Total synthesis of the Fusarium toxin Equisetin" L.
Agglomerin A and (±)-carolinic acid A variety of O-methyl-3-acyl tetronates were prepared in good yield from the corresponding acid chlorides via a palladium catalyzed acylation of O-methyl 3-(tri-n-butylstannyl) tetronates. This new synthetic method was then exploited for the total synthesis of the novel antibiotic agglomerin A, as well as the fungal metabolite (±) carolinic acid. See: S.V. Ley, M.L. Trudell, D.J. Wadsworth, Tetrahedron, 1991, 47, 8285.
Generally, ritual order and religion which are essentially based on categorical values of a traditional nature do not show evidence of decline, nor is there an easy possibility of their disappearance in the near future.
Modernization, cultural change, and the persistence of traditional values.
02/04/2002 · The total synthesis of the ..
"An oxidative coupling for the synthesis of arylated quaternary stereocentres and its application in the total synthesis of powelline and buphanidrine" K.
total synthesis of (+)-goniodiol…
"Efficient and selective formation of macrocyclic disubstituted Z alkenes by ring-closing metathesis (RCM) reactions catalyzed by Mo- or W-based monoaryloxide pyrrolide (MAP) complexes: Applications to total syntheses of epilachnene, yuzu lactone, ambrettolide, epothilone C, and nakadomarin A" C.
Enantioselective total synthesis of (+) ..
641. Total Synthesis Studies Towards the Macrocyclic Pipercolic Natural Products FK 506, Antascomycins and Rapamycin M.L. Maddess, M.N. Tackett and S.V. Ley, “Progress in Drug Research Vol 66: Natural Compounds as Drugs, Vol. II Eds. F. Peterson and R. Amstutz, 2008, Birkhauser Verlag AG Basel ISBN:978-3-7643-8594. P13-186.
A total synthesis of (+)-Goniodiol using an anomeric ..
CP-61,405 (routiennocin) The total synthesis of the spiroketal ionophore antibiotic routiennocin (CP-61,405) employing π-allyltricarbonyl iron lactone complexes is described. These complexes were used as precursors for the preparation of substituted 2-phenylsulphonyl pyrans which, in turn, were coupled with iodoacetonides to afford spiroketals. Elaboration of the spiroketals by tetra-n-propylammonium perruthenate (TPAP) oxidation and coupling with 2-lithio-1-[beta-(trimethylsilyl)ethoxymethyl] pyrrole followed by further oxidation, deprotection, oxidation and benzoxazole formation afforded the natural product. The preparation of the amino phenol fragment necessary for benzoxazole formation involved a novel amination procedure using benzeneselenenic anhydride and hexamethyldisilazane followed by samarium diiodide reduction. See: D. Díez-Martin, N.R. Kotecha, S.V. Ley, S. Mantegani, J.C. Menéndez, H.M. Organ, A.D. White, B.J. Banks, Tetrahedron, 1992, 48, 7899; D. Diez-Martin, N.R. Kotecha, S.V. Ley, J.C. Menendez, Synlett, 1992, 399 and N.R. Kotecha, S.V. Ley, S. Mantegani, Synlett, 1992, 395.
A Highly Enantioselective Total Synthesis of (+)-Goniodiol ..
(+)-Milbemycin a1 The total synthesis of the antiparasitic spiroketal macrolide (+)-milbemycin a1 is reported, following Julia sulfone anion coupling of the sulfone 3 with a northern hemisphere aldehyde 2 and subsequent functional group elaboration. See: S. V. Ley, A. Madin and N. Monck, Tetrahedron Lett. 1993, 34, 7479.