4-Nitrophenol CAS 100-02-7 | 814558
Nitrophenols (nitrophenols MW 139, DNPs MW 184) are also antigenic. A large fraction of the entire human population has circulating antibodies reactive towards nitrophenols. (If I had lit access, I’d provide more specific numbers.) Spiegel (Yale) couples nitrophenols to targeting ligands to bind to specific receptors that will then recruit the nitrophenol existing Abs to kill the targeted cells.
Optimization of Synthesis of 2-Ethoxy-4-Nitrophenol
4-Nitrophenol (also called p-nitrophenol or 4-hydroxynitrobenzene) is a phenolic compound that has a nitro group at the opposite position of hydroxy group on the benzene ring.
4-Nitrophenol is an intermediate in the synthesis of paracetamol. It is reduced to 4-aminophenol, then acetylated with acetic anhydride.
4-Nitrophenol is used as the precursor for the preparation of phenetidine and acetophenetidine, indicators, and raw materials for fungicides. Bioaccumulation of this compound rarely occurs.
Solution of 4-nitrophenol alone appears colorless or pale yellow, whereas its phenolic salts tend to develop a bright yellow color. This color-changing property makes this compound useful as a pH indicator.
was used to study the electrochemical sensing of 4-nitrophenol ..
4-Nitrophenol is used to manufacture drugs (as an intermediate in the synthesis of paracetamol, 4-nitrophenol is reduced to 4-aminophenol, then acetylated with acetic anhydride).
4-Nitrophenol is an intermediate in the synthesis of paracetamol
AB - A green and cost-effective biosynthetic approach for the preparation of icosahedral gold nanoparticles (AuNPs) using an aqueous leaf extract of Polygonum minus as reducing and stabilising factor is described. The reduction of Au3+ ions to elemental Au rapidly occurred and is completed within 20 minutes at room temperature. The size of the nanoparticles is highly sensitive to the AuCl4 −/leaf extract concentration ratio and pH. Transmission electron microscopy and X-ray diffraction data indicated that the nanoparticles were in a crystalline shape (face-centred cubic), mostly icosahedral and nearly monodispersed with an average size of 23 nm. Cyclic voltammetric studies suggested that flavonoids, such as quercetin and myricetin present in the leaf extract had a tendency to donate electrons to Au3+ ions and the formation of elemental Au was possible due to the transfer of electrons from these flavonoids to Au3+ ions. Infrared absorption of the AuNPs and the leaf extract revealed that the oxidised (quinone) form of quercetin and myricetin were presumably the main stabilising agents in the formation of stable nanoparticles. The present biosynthesis of AuNPs was simple, rapid, cost-effective and environmentally friendly. The newly prepared biostabilised icosahedral AuNPs show good catalytic activity in the reduction of 4-nitrophenol (4-NP) to 4-aminophenol (4-AP).
A mixture of 94 grams of phenol and 20 ml
Ye, W.; Yu, J.; Zhou, Y.; Gao, D.; Wang, D.; Wang, C.; Xue, D. Green synthesis of Pt-Au dendrimer-like nanoparticles supported on polydopamine-functionalized graphene and their high performance toward 4- nitrophenol reduction. Appl. Catal., B 2015, 181, 371-378.
Is there any way in which we can synthesize para-nitrophenol only
Chaudhary, S.; Kumar, S.; Mehta, S. K. Glycol modified gadolinium oxide nanoparticles as a potential template for selective and sensitive detection of 4-nitrophenol. J. Mater. Chem. C 2015, 3 (34), 8824-8833.